P-749 Increased accuracy in infertility workup by the additional use of new modern diagnostic methods (“diagnostic TRIO”): results from a large retrospective analysis

Abstract Study question Is there any positive effect of adding new modalities to the traditional infertility work-up, like 3D sonography, office hysteroscopy and endometrial biopsy? Summary answer During workup conventional diagnostic tests should be combined with approaches (3D-TVS, OHSC biopsy) achieve more accurate less invasive diagnostics. What is known already Female can explained by functional or organic abnormalities affecting reproductive system. The most common causes include within uterine cavity (e.g. polyp, submucosal fibroid, intrauterine adhesion), morphological disorders dysmorphic uterus, septum) endometrium chronic endometritis). design, size, duration In our retrospective study, we examined patients primary secondary infertility. All were assessed 3D-TVS detect disorders, in special cases (repeated implantation failure – RIF), biopsies carried out disorders. Participants/materials, setting, methods Data 606 between 2018 2022 analyzed retrospectively. Main results role chance performed (65.51 % primary, 34.49 infertility), who had unknown reason By combination could verify 39.93 cases. Together these two found probable causing lesion almost 40 patients. subgroup repeated (RIF) patients, “diagnostic TRIO” confirmed a disorder 57.50 Limitations, reasons for caution Number conclude data. Wider implications findings proper condition milieu, through correction if necessary, receptivity are paramount importance success treatment; as result, surgery subspecialty has been developing. Trial registration number DE RKEB/IKEB: H.0250-2020